“What should I do if I get a fever・pain in Japan?”

1. Acetaminophen (アセトアミノフェン)

• 2. Product Names in Japan: Tylenol A, Calonal

• 3. Common Overseas Names: Tylenol, Panadol

• 4. Who Should Be Careful:

　• Those with liver problem.
・5. What Symptoms It Can Be Used For

　For pain and fever:

　It is less effective in reducing inflammation compared to other antipyretic and analgesic medications but has fewer side effects, such as gastrointestinal issues.

6. Where to Buy It:
　OTC medication, available at most drugstores.

It is commonly used in Japan as an antipyretic and analgesic for children.

Both medications in the image on the right contain 300mg per tablet.

1. Ibuprofen (イブプロフェン)

• 2. Product Names in Japan: Eve (Eve A, Eve Quick), Bufferin Premium

• 3. Common Overseas Names: Advil, Nurofen

• 4. Who Should Be Careful:

• People with stomach ulcers or a history of gastric issues

• Those with kidney problems

・Pregnant women in their third trimester

　Individuals undergoing aspirin antiplatelet therapy (for heart disease) have been reported to have potential interactions.

・5. What Symptoms It Can Be Used For
　A common antipyretic and analgesic, it has stronger anti-inflammatory effects than acetaminophen and shows good transfer to the uterus.

6. Where to Buy It:
　OTC medication, available at most drugstores.

It is commonly used for children under 15 in other countries, but in Japan, it is not approved for use as an OTC medication.

It is not sold as a single-ingredient product; it is combined with other ingredients, such as caffeine, in compound formulations.

1. Aspirin (アセチルサリチル酸)

• 2. Product Names in Japan: Bufferin, Bayaspirin

• 3. Common Overseas Names: Aspirin, Bayer

• 4. Who Should Be Careful:

• Children and teenagers (risk of Reye’s syndrome)

• People with bleeding disorders

・Pregnant women in their third trimester

・People taking low-dose aspirin for heart disease, cerebrovascular disease, or similar conditions.

・5. What Symptoms It Can Be Used For
・It is commonly used as an antipyretic and analgesic for individuals aged 15 and older.

6. Where to Buy It:
　OTC medication, available at most drugstores.

Aspirin is rarely available as a single-ingredient product. It is often combined with other medications.

The product on the left in the image is a combination of aspirin and a gastric mucosal protective agent. Among over-the-counter medications, it is likely the simplest formulation.

1. Loxoprofen (ロキソプロフェン)

• 2. Product Names in Japan: Loxonin S

• 3. Common Overseas Names: Not commonly available overseas in OTC form

• 4. Who Should Be Careful:

• People with a history of stomach issues

• Children and teenagers (risk of Reye’s syndrome)

• Pregnant women (especially in the third trimester)

・5. What Symptoms It Can Be Used For
・In Japan, it is the most well-known antipyretic and analgesic used for individuals aged 15 and older.

6. Where to Buy It:
・This medication can only be sold by a licensed pharmacist.

Please purchase it at a store where a pharmacist is available. Note that not all drugstores have a pharmacist on staff.

Since this medication was developed by a Japanese company, it may not be well-known overseas, but it is widely recognized within Japan.

The blue one is a single-ingredient medication, while the others are combination drugs.

The pink one is a combination that includes magnesium oxide (as an antacid).